Publications

Selected scientific publications on diving medicine and physiology.

2014 Mar 1
Association of digital vascular function with cardiovascular risk factors: a population study.
Kuznetsova T, Van Vlierberghe E, Knez J, Szczesny G, Thijs L, Jozeau D, Balestra C, D'hooge J, Staessen JA.

OBJECTIVES: Vasodilation of the peripheral arteries during reactive hyperaemia depends in part on release of nitric oxide from endothelial cells. Previous studies mainly employed a fingertip tonometric device to derive pulse wave amplitude (PWA) and PWA hyperaemic changes. An alternative approach is based on photoplethysmography (PPG). We sought to evaluate the correlates of digital PPG PWA hyperaemic responses as a measure of peripheral vascular function...

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2014 Mar 1
The "normobaric oxygen paradox": a new tool for the anesthetist?
Rocco M, D'Itri L, De Bels D, Corazza F, Balestra C.

Hypoxia is the natural trigger for endogenous EPO production but recently the use of intermittent hyperoxia to stimulate EPO has been postulated and this phenomenon has been called the "normobaric oxygen paradox" (NOP). The "NOP" is a mechanism by which oxygen regulates the expression of the Hypoxia Inducible Factor 1 alpha (HIF-1α)...

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2014 Mar 1
The use of portable 2D echocardiography and 'frame-based' bubble counting as a tool to evaluate diving decompression stress
Germonpré P, Papadopoulou V, Hemelryck W, Obeid G, Lafère P, Eckersley RJ, Tang MX, Balestra C.

INTRODUCTION: 'Decompression stress' is commonly evaluated by scoring circulating bubble numbers post dive using Doppler or cardiac echography. This information may be used to develop safer decompression algorithms, assuming that the lower the numbers of venous gas emboli (VGE) observed post dive, the lower the statistical risk of decompression sickness (DCS). Current echocardiographic evaluation of VGE, using the Eftedal and Brubakk method, has some disadvantages as it is less well suited for large-scale evaluation of recreational diving profiles. We propose and validate a new 'frame-based' VGE-counting method which offers a continuous scale of measurement...

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2014 Feb 1
Bubble stream reveals functionality of the right-to-left shunt: detection of a potential source for air embolism
Parlak IB, Egi SM, Ademoglu A, Germonpré P, Esen OB, Marroni A, Balestra C.

The existence of a right-to-left shunt may increase the likelihood of micro-embolism by allowing a flux of bubbles under hyperbaric conditions. The aim of the study was to measure the relationship between these shunts and bubbles in 10 consecutive subjects using trans-thoracic and trans-esophageal echocardiography...

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2013 Dec 3
Dark chocolate reduces endothelial dysfunction after successive breath-hold dives in cool water
Theunissen S, Schumacker J, Guerrero F, Tillmans F, Boutros A, Lambrechts K, Mazur A, Pieri M, Germonpré P, Balestra C.

OBJECTIVE: The aim of this study is to observe the effects of dark chocolate on endothelial function after a series of successive apnea dives in non-thermoneutral water...

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