Wetenschappelijke artikelen
Geselecteerde wetenschappelijke artikelen over duikgeneeskunde en -fysiologie
2015 jan 22
Genetic predisposition to breath-hold diving-induced hemoptysis: Preliminary study
Cialoni D, Marabotti C, Sponsiello N, Pieri M, Balestra C, Lucchini V, Marroni A.

INTRODUCTION: Breath-hold diving-induced hemoptysis (BH-DIH) has been reported in about 25% breath-hold divers (BHD) and is characterized by dyspnea, coughing, hemoptysis and chest pain. We investigated whether eNOS G894T, eNOS T786C and ACE insertion/deletion I/D genetic variants, are possible BH-DIH risk factors...

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1996 jan 1
HBO Dose Titration
Marroni A, Oriani G, Longoni C.

The clinical application of Hyperbaric Oxygen Therapy (HBOT), although based on sound physiological principles as well as on a logical rationale, has often been characterized by empirical procedures, and the choice of the treatment schedules has been more fortuitous than rational. The indication for HBOT and the treatment protocol are originated by the general and often acritical assumption that a given lesion or malfunction is caused, facilitated or worsened by hypoxia. Furthermore, the increasingly common use of multiplace hyperbaric chambers, where many patients can be treated at the same time, although maximizing the cost benefit ration of HBOT and the performance of the chamber technical and nursing personnel justified the commonly adopted routine of using average treatment pressures and schedules without considering the differences between indications, patients, disease conditions and the evolving physiopathological stages of the healing process in the individual patients. As a consequence, it is quite frequent to witness the very strange paradox that a treatment based on extremely solid physiological grounds is often applied empirically and nonrationally.

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2015 jul 1
Heart rate variability and critical flicker fusion frequency changes during and after parachute jumping in experienced skydivers.
Cavalade, Papadopoulou V, Theunissen S, Balestra C.

PURPOSE: The purpose of this study was (1) to further explore the heart rate dynamics and assess a potential cardiovascular risk in response to 4000 m jumps in experienced skydivers; (2) to assess whether there is an impact of such jumps on skydivers' cortical arousal or not, which may impact their decision making processes...

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2021 jul 26
Heart Rate Variability during a standard dive: a role for inspired oxygen pressure?
Pierre Lafère, Kate Lambrechts, Peter Germonpre, Ambre Balestra, Faye Lisa Germonpré, Alessandro Marroni, Danilo Cialoni, Gerardo Bosco, Costantino Balestra

Introduction: Heart rate variability (HRV) during underwater diving has been infrequently investigated because of environment limitations and technical challenges. This study aims to analyze HRV changes while diving at variable hyperoxia when using open circuit (OC) air diving apparatus or at constant hyperoxia using a closed-circuit rebreather (CCR).

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2018 aug 21
Hemoglobin and Erythropoietin After Commercial Saturation Diving
Kiboub FZ., Balestra C., Loennechen Ø., Eftedal I.

Saturation divers are exposed to elevated partial pressure of oxygen (ppO2) in their hyperbaric work environment. Experimental studies indicate that oxygen transport is altered, and we have previously reported a drop in hematocrit and extensive downregulation of genes involved in blood oxygen transport capacity after decompression from professional saturation diving. Here we investigate the initial period of hematological adjustment back to normobaric air after professional saturation diving. Erythropoietin (EPO) and hemoglobin (Hb) were measured in blood from 13 divers at two time-points after saturation assignments lasting up to 4 weeks; first immediately after decompression and again 24 h later. Pre-dive levels defined baselines.

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