2019 feb 21
Altered Venous Blood Nitric Oxide Levels at Depth and Related Bubble Formation During Scuba Diving
Introduction: Nitric oxide (NO) plays an important role in the physiology and pathophysiology of diving, and the related endothelial dysfunction and oxidative stress roles have been extensively investigated. However, most available data have been obtained before and after the dive, whilst, as far as we know, no data is available about what happens during the water immersion phase of dive. The scope of this study is to investigate the Nitrate and Nitrite (NOX) concentration and the total plasma antioxidant capacity (TAC) before, during and after a single SCUBA dive in healthy scuba diving volunteers, as well as to look for evidence of a possible relationship with venous gas bubble formation.
Materials and Methods: Plasma, obtained from blood of 15 expert SCUBA divers, 13 male and 2 female, was investigated for differences in NOX and TAC values in different dive times. Differences in NOX and TAC values in subjects previously known as "bubble resistant" (non-bubblers - NB) and "bubble prone" (Bubblers - B) were investigated.