Pubblicazioni
Pubblicazioni scientifiche selezionate sulla medicina e la fisiologia subacquea
2021 ago 25
Physiological effects of mixed-gas deep sea dives using a closed-circuit rebreather: a field pilot study
Dugrenot E, Balestra C, Gouin E, L'Her E & Guerrero F.

Purpose: Deep diving using mixed gas with closed-circuit rebreathers (CCRs) is increasingly common. However, data regarding the effects of these dives are still scarce. This preliminary field study aimed at evaluating the acute effects of deep (90-120 msw) mixed-gas CCR bounce dives on lung function in relation with other physiological parameters. Methods: Seven divers performed a total of sixteen open-sea CCR dives breathing gas mixture of helium, nitrogen and oxygen (trimix) within four days at 2 depths (90 and 120 msw). Spirometric parameters, SpO2, body mass, hematocrit, short term heart rate variability (HRV) and critical flicker fusion frequency (CFFF) were measured at rest 60 min before the dive and 120 min after surfacing.

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2010 gen 2
Pre-dive vibration effect on bubble formation after a 30-m dive requiring a decompression stop
Germonpré P1, Pontier JM, Gempp E, Blatteau JE, Deneweth S, Lafère P, Marroni A, Balestra C.

INTRODUCTION: The preconditioning of divers to reduce post-dive decompression sickness (DCS) has gained increased interest in diving medical research over the last few years. The beneficial effects of physical exercise, oxygen breathing, hyperbaric exposure, heat exposure, hyperhydration, or nitroglycerin administration before the dive are only a few examples of ongoing research. In this work, we investigated the effects of pre-dive whole-body vibration on post-dive bubble formation.

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2016 dic 30
Pre-dive Whole-Body Vibration Better Reduces Decompression-Induced Vascular Gas Emboli than Oxygenation or a Combination of Both
Balestra C., Theunissen S., Papadopoulou V., Le Mener C., Germonpré P., Guerrero F., Lafère P.

Purpose: Since non-provocative dive profiles are no guarantor of protection against decompression sickness, novel means including pre-dive “preconditioning” interventions, are proposed for its prevention. This study investigated and compared the effect of pre-dive oxygenation, pre-dive whole body vibration or a combination of both on post-dive bubble formation.

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2014 dic 1
Preconditioning as a tool to improve diving safety
Balestra C, Blatteau J, Gempp E & Rozloznik M

Vascular gas bubbles are considered the principal element in decompression sickness (DCS) development. Traditionally these bubbles were called VGE (venous gas emboli), however scientific knowledge indicates that similar bubbles may also be present in the arterial circulation, therefore we propose to use “VGE” for “Vascular Gas Emboli”, and we will do so throughout the text. Reduction of VGE production represents an interesting endpoint to decrease decompression stress and DCS risk. Here we will discuss state of the art pre-dive techniques and approaches, commonly known as preconditioning, used to reduce post-dive VGE load and decompression stress. Evidence based approaches clearly show that some types of preconditioning are more potent in VGE reduction, some indecompression stress reduction and there are some with a positive impact on both. Nevertheless, further research is required to investigate the mechanisms underlying these positive effects.

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2017 feb 1
Preconditioning to Reduce Decompression Stress in Scuba Divers
Germonpré P., Balestra C.

BACKGROUND: Using ultrasound imaging, vascular gas emboli (VGE) are observed after asymptomatic scuba dives and are considered a key element in the potential development of decompression sickness (DCS). Diving is also accompanied with vascular dysfunction, as measured by flow-mediated dilation (FMD). Previous studies showed significant intersubject variability to VGE for the same diving exposure and demonstrated that VGE can be reduced with even a single pre-dive intervention. Several preconditioning methods have been reported recently, seemingly acting either on VGE quantity or on endothelial inflammatory markers.

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