Publikationen
Ausgewählte wissenschaftliche Publikationen aus den Bereichen Tauchmedizin und Tauchphysiologie.
2022 Jul 17
Varying Oxygen Partial Pressure Elicits Blood-Borne Microparticles Expressing Different Cell-Specific Proteins microparticles;Toward a Targeted Use of Oxygen?
Balestra C, Arya AK, Leveque C, Virgili F, Germonpré P, Lambrechts K, Lafère P & Thom SR.

Oxygen is a powerful trigger for cellular reactions, but there are few comparative investigations assessing the effects over a large range of partial pressures. We investigated a metabolic response to single exposures to either normobaric (10%, 15%, 30%, 100%) or hyperbaric (1.4 ATA, 2.5 ATA) oxygen.

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2022 Apr 28
Effects of Acute Hypobaric Hypoxia Exposure on Cardiovascular Function in Unacclimatized Healthy Subjects: A "Rapid Ascent" Hypobaric Chamber Study
Theunissen S, Balestra C, Bolognési S, Borgers G, Vissenaeken D, Obeid G, Germonpré P, Honoré PM & De Bels D.

Background: This study aimed to observe the effects of a fast acute ascent to simulated high altitudes on cardiovascular function both in the main arteries and in peripheral circulation. Methods: We examined 17 healthy volunteers, between 18 and 50 years old, at sea level, at 3842 m of hypobaric hypoxia and after return to sea level. Cardiac output (CO) was measured with Doppler transthoracic echocardiography.

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2022 Jan 1
Post-decompression bubble and inflammation interactions: a non-extensive dynamical system model
Schirato SR, Silva V, Iadocicco K, Maronni A, Pieri M, Cialoni D & Chaui-Berlinck JG.

Inert gas bubbles in tissues and in blood have been historically considered as the only triggering factors for DCS, but now many other factors are considered to affect the final outcome of a decompression profile for a certain individual. In this sense, inflammation seems to play a relevant role, not only due to the physical damage of tissues by the bubbles, but as a potentiator of the process as a whole. The present study aims to put forward a mathematical model of bubble formation associated with an inflammatory process related to decompression.

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2022 Apr 29
Mini Trampoline, a New and Promising Way of SCUBA Diving Preconditioning to Reduce Vascular Gas Emboli?
Lambrechts K, Germonpré P, Vandenheede J, Delorme M, Lafère P & Balestra C.

Background: Despite evolution in decompression algorithms, decompression illness is still an issue nowadays. Reducing vascular gas emboli (VGE) production or preserving endothelial function by other means such as diving preconditioning is of great interest. Several methods have been tried, either mechanical, cardiovascular, desaturation aimed or biochemical, with encouraging results. In this study, we tested mini trampoline (MT) as a preconditioning strategy.

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2022 Jan 21
Oxidative stress and motion sickness in one crew during competitive offshore sailing
Giacon TA, Bosco G, Vezzoli A, Dellanoce C, Cialoni D, Paganini M & Mrakic-Sposta S.

Competitive Offshore Ocean Sailing is a highly demanding activity in which subjects are exposed to psychophysical stressors for a long time. To better define the physiological adaptations, we investigated the stress response of subjects exposed to 3-days long ocean navigation with disruption of circadian rhythms.

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